Pfhrp2 Deletions in the Democratic Republic of Congo: Evidence of Absence, or Absence of Evidence?
نویسندگان
چکیده
Financial support. This work was supported by the National Institute of Allergy and Infectious Diseases (grants 5T32AI007151 to J. B. P. and 5R01AI107949 to S. R. M.). Potential conflicts of interest. Both authors: No reported conflicts of interest. Both authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.
منابع مشابه
Modelling the drivers of the spread of Plasmodium falciparum hrp2 gene deletions in sub-Saharan Africa
Rapid diagnostic tests (RDTs) have transformed malaria diagnosis. The most prevalent P. falciparum RDTs detect histidine-rich protein 2 (PfHRP2). However, pfhrp2 gene deletions yielding false-negative RDTs, first reported in South America in 2010, have been confirmed in Africa and Asia. We developed a mathematical model to explore the potential for RDT-led diagnosis to drive selection of pfhrp2...
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عنوان ژورنال:
دوره 216 شماره
صفحات -
تاریخ انتشار 2017